你应该使用什么类型的 PQQ?

0 Comments

PQQ: Boost The Energy In Your Cells To Do Everything Better

提高你细胞的能量,让所有事情做得更好

  • Dave Asprey 戴夫 · 阿斯普雷

Affiliate Disclosure & Health Claims

附属公司披露和健康索赔

pqq supplements

If you’re looking for a way to upgrade your mitochondria and boost your energy with zero crash, look no further than PQQ, or pyrroloquinoline quinone, a supplement on the forefront of anti-aging science. Anti-aging starts at the cellular level and PQQ is an easy way to protect your cells, all while helping to improve the most mitochondrial-dense parts of your body like your brain and heart.

如果你正在寻找一种升级你的线粒体和提高你的能量零崩溃的方法,看看 PQQ,或吡咯并喹啉醌,一个抗衰老科学前沿的补充剂。抗衰老始于细胞水平,PQQ 是一种保护细胞的简单方法,同时有助于改善你身体中像大脑和心脏这样线粒体密度最高的部位。

What is PQQ?

什么是 PQQ?

PQQ is a micronutrient that acts as an antioxidant in your body, protecting your cells (and specifically your mitochondria) from damaging free radicals. Most of the research around it has to do with mitochondrial density and function, which is why I found it so fascinating when I started researching supplements years ago. The more mitochondria you have and the better they function, the more energy and longevity you can expect.

PQQ 是一种微量营养素,在你的身体中起到抗氧化剂的作用,保护你的细胞(特别是你的线粒体)免受有害的自由基的伤害。围绕它的大多数研究都与线粒体密度和功能有关,这就是为什么我几年前开始研究补充剂时发现它如此迷人的原因。线粒体数量越多,功能越好,你可以期待的能量和寿命就越长。

You can find PQQ naturally in many foods, but not in super high amounts. It’s especially high in green tea, fermented soy (natto), spinach parsely, and green peppers.[1] However, the more I learn about PQQ supplementation, the more I suggest taking it in higher amounts than you can find in a salad.

你可以在许多食物中自然地找到 PQQ,但不是超高的含量。它在绿茶、豆豉、菠菜和青椒中含量特别高。[1]然而,我对 PQQ 补充剂了解得越多,我就越建议服用比沙拉中含量更高的 PQQ 补充剂。

PQQ and Your Mitochondria

PQQ 和你的线粒体

Mitochondria are the tiny organelles working to produce cellular ATP, or adenosine triphosphate, the energy currency of your cells. All the energy in your body – your movements, your breath, and your thoughts – ultimately come from mitochondria. Mitochondria are in every cell in your body, but mitochondrial density is greatest in the areas of your body that require the most energy, like your brain and your heart. That’s why a lot of the science around PQQ is for brain and heart function. And it’s showing some really promising results.

线粒体是一种微小的细胞器,负责产生细胞内的 ATP,或者说三磷酸腺苷—- 细胞内的能量货币。你身体里的所有能量——你的动作、你的呼吸和你的思想——最终都来自线粒体。线粒体存在于你身体的每个细胞中,但是线粒体密度最高的是你身体中需要最多能量的区域,比如你的大脑和你的心脏。这就是为什么许多围绕 PQQ 的科学研究都是关于大脑和心脏功能的。它显示了一些非常有前途的结果。

Mitochondrial dysfunction, on the other hand, is one of the main biomarkers of aging and disease. In fact, researchers can link mitochondrial dysfunction with nearly every disease associated with aging, from Alzheimer’s to heart failure. The good news is, you can make your mitochondria stronger.

另一方面,线粒体功能障碍是衰老和疾病的主要生物标志物之一。事实上,研究人员可以将线粒体功能障碍与几乎所有与衰老有关的疾病联系起来,从老年痴呆症到心力衰竭。好消息是,你可以让你的线粒体更强壮。

My own mitochondrial function has been a focus of biohacking for years. A huge number of the things I do have a direct impact on how mitochondria work. Things like ketosisBrain Octane Oilhigh-intensity exerciseBulletproof intermittent fasting, and avoiding the toxins that make you weak all help strengthen your mitochondria and create new ones.

多年来,我自己的线粒体功能一直是生物黑客研究的焦点。我做的很多事情都直接影响着线粒体的工作。像酮症,脑辛烷油,高强度运动,防弹间歇性禁食,避免毒素,使你虚弱,所有这些都有助于加强你的线粒体和创造新的。

If you find a way to improve your mitochondrial function, you’ll make energy more efficiently. One of the most exciting ways I’ve found of increasing mitochondrial function is the compound pyrroloquinoline quinone.

如果你能找到一种方法来改善你的线粒体功能,你就能更有效地制造能量。我发现提高线粒体功能最令人兴奋的方法之一是吡咯并喹啉醌。

The Benefits of PQQ

PQQ 的好处

There is a lot of research (note that most of these studies are in rats) supporting PQQ’s ability to kick your mitochondria into high gear. Specifically, research shows it can:

有很多研究(注意,大多数这些研究都是在老鼠身上进行的)支持 PQQ 的能力,使你的线粒体高速运转。具体来说,研究表明它可以:

  • Increase mitochondrial density to give you more energy 增加线粒体密度,给你更多的能量[2]
  • Reduce inflammation 减少炎症[3]
  • Boost metabolism 促进新陈代谢[4]
  • Combat oxidative stress 战斗氧化应激[5]
  • Improve fertility 提高生育率[6]
  • Improve learning and memory ability 提高学习和记忆能力[7]
  • Protect your heart 保护你的心脏[8]

How PQQ Works

PQQ 是如何工作的

One of the most impressive qualities of PQQ in humans is its antioxidant effects. It’s about 100 times as powerful as vitamin C and increases Nrf2, a critical pathway that increases natural antioxidant production.[9][10][11]  

PQQ 在人体中最令人印象深刻的特性之一是它的抗氧化作用。它的功效大约是维生素 c 的100倍,并且增加 Nrf2,一种增加天然抗氧化剂产生的关键途径。[10][11]

PQQ is also known for preventing the development of damaging proteins associated with Parkinson’s disease and can stimulate the release of nerve growth factor cells in the brain.[12]

PQQ 还可以防止与帕金森病相关的破坏性蛋白质的产生,并且可以刺激大脑中神经生长因子细胞的释放。[12]

PQQ also affects the way your genes work. That’s right, it can activate the PGC-1a gene, sparking mitochondrial biogenesis (aka the growth of new mitochondria).[13][14][15] This is one of the main reasons I teach people that it’s never too late to start biohacking. You can actually repair and regrow your mitochondria!

PQQ 也会影响你的基因工作方式。没错,它可以激活 PGC-1a 基因,引发线粒体生物合成(即新线粒体的生长)。这是我告诉人们开始生物黑客行动永远不会太晚的主要原因之一。你可以修复和再生你的线粒体!

What Type of PQQ Should You Take?

你应该使用什么类型的 PQQ?

I started taking 30-40mg of the common form of PQQ every day years ago. However, unlike other mitochondrial energizers, I never felt any effect. It’s possible it was doing something, but nothing detectable. PQQ is an expensive supplement, and I’m now convinced I was wasting my money and time on it.

几年前,我开始每天服用30-40毫克普通型的 PQQ。然而,与其他线粒体增能剂不同的是,我从未感觉到任何效果。有可能它在做什么,但是什么也检测不到。PQQ 是一种昂贵的补充剂,我现在确信我在它上面浪费了我的金钱和时间。

The likely reason I didn’t feel any energy from large doses over an extended time is that it is sold as the “stabilized” disodium salt form because it’s more convenient for the manufacturer. Unfortunately, in humans, disodium salts precipitate when they are exposed to even small amounts of stomach acid. That means all that expensive PQQ I took was turning into little rocks in my stomach, and not helping my mitochondria the way I wanted it to.

可能的原因我没有感觉到任何能量从大剂量超过一个较长的时间是,它是作为“稳定”二钠盐形式出售,因为它更方便的制造商。不幸的是,在人体中,二钠盐在暴露于少量胃酸时会沉淀下来。这意味着我服用的昂贵的 PQQ 在我的胃里变成了小石头,并且没有按照我想要的方式帮助我的线粒体。

PQQ Salt Verses Active PQQ

盐和活跃的 PQQ

So what’s a biohacker to do?

那么生物黑客该怎么做呢?

You know what they say…if you want it done right…

你知道他们怎么说的… 如果你想把事情做好..。

I set out to synthesize PQQ directly, targeting an acid form of PQQ that would be at home in stomach acid, and bypass the problem with standard PQQ supplements. That is how ActivePQQ was born. ActivePQQ is the main ingredient in one of my favorite supplements to date: Unfair Advantage.

我开始直接合成 PQQ,针对一种酸性的 PQQ,这种 PQQ 可以在家里的胃酸中使用,并且通过标准的 PQQ 补充剂绕过了这个问题。这就是 ActivePQQ 的诞生。ActivePQQ 是迄今为止我最喜欢的一种补充剂的主要成分: 不公平的优势。

ActivePQQ improves PQQ absorption by creating a pre-colloidal and colloidal suspension with particle sizes so small they remain suspended in water. Unfair Advantage uses colloids – permanently suspended nanoparticles – of ActivePQQ and CoQ10 to create a supplement that activates mitochondria so powerfully that you can feel it work very quickly.

ActivePQQ 提高 PQQ 的吸收,通过创造前胶体和胶体悬浮颗粒大小很小,他们仍然悬浮在水中。“不公平优势”使用 ActivePQQ 和 CoQ10的胶体——永久悬浮的纳米粒子——来制造一种补充剂,它能有力地激活线粒体,让你感觉它工作得非常快。

ActivePQQ and CoQ10 work well together as colloids because the CoQ10 helps the PQQ absorb – that’s why there’s a 2:1 ratio of CoQ10 to ActivePQQ. (I recommend you take larger doses of CoQ10 separately too!)

ActivePQQ 和 CoQ10作为胶体一起工作得很好,因为 CoQ10有助于 PQQ 的吸收——这就是为什么 CoQ10和 ActivePQQ 的比例是2:1。(我建议你也单独服用大剂量的辅酶 q10!)

Unfair Advantage is the most important supplement I’ve ever created, and I’m really excited about it.

不公平优势是我做过的最重要的补充,我对此感到非常兴奋。

You owe it to yourself to take care of your mitochondria because mitochondrial dysfunction is behind nearly every degeneration that happens as you age. Whether or not you use Unfair Advantage, make sure you do something to grow your mitochondria and keep them healthy, like heavy resistance training, Bulletproof Intermittent fasting, cold thermogenesis, Brain Octane Oil, or even bright red LED light therapy.

你有责任照顾好自己的线粒体,因为随着年龄的增长,几乎每一次退化背后都有线粒体功能障碍。不管你是否使用了不公平优势,确保你做了一些事情来增加你的线粒体并保持它们的健康,比如重度抵抗训练,防弹间歇性禁食,冷生热,脑辛烷油,甚至亮红色 LED 灯治疗。

Strong mitochondria make for strong people!

强壮的线粒体造就强壮的人!

Rea

发表评论

您的电子邮箱地址不会被公开。 必填项已用*标注